Kyphon and the X-STOP® IPD® Procedure to be Featured on American Health Radio on
Monday, September 24, 2007

New Minimally Invasive Procedure for Treating Major Symptoms of Lumbar Spinal Stenosis

SUNNYVALE, California · September 18, 2007 /PRNewswire/ — Kyphon Inc. (Nasdaq:KYPH) today announced that Dr. Michael Marks, orthopaedic spine surgeon from Coastal Orthopedics in Norwalk, Connecticut, and Julie Tracy, Kyphon's chief communications officer, will be interviewed together on American Health Radio, the nationally-syndicated health radio program hosted by Scott Broder. The program will include questions from listeners on the role of the X-STOP® Interspinous Process Decompression (IPD®) procedure to treat the symptoms of lumbar spinal stenosis.

During the show, Dr. Marks will discuss the treatment options available to patients suffering from lumbar spinal stenosis, including the X-STOP® implant, the first interspinous process spacer approved in the U.S. for treating the symptoms of lumbar spinal stenosis. Symptoms from lumbar spinal stenosis often limit a patient's self-supporting daily activities, work, and social and recreational pursuits. Using a minimally invasive surgical procedure to place the X-STOP® implant, symptoms may be relieved, and patients may return to a more active lifestyle.

The program will air live at 6:00 p.m. Central Time on Monday, September 24, 2007 and can be accessed at www.wrmn1410.com. A replay of the program will be available on Wednesday, September 26 at 8:00 p.m. Central Time and on Friday, September 28 at 6:00 p.m. Central Time. Repeat broadcasts will also be available at www.healthradionetwork.com.

About the X-STOP® IPD® Procedure

The X-STOP® IPD® procedure represents a new approach to treating the symptoms of lumbar spinal stenosis or LSS. LSS is a common spinal problem suffered mainly by the middle-aged and elderly population and results from a narrowing in the lumbar spinal canal that carries nerves to the legs. As this space in the lower spine shrinks, nerves are squeezed causing debilitating pain in the back and legs.

The X-STOP® implant is the first approved Interspinous Process Spacer in the U.S. to treat the symptoms of LSS. It is designed to limit extension of the lumbar spine and keep the canal open in the lower spine that carries nerves to the legs thereby relieving pain associated with the narrowing of the canal.

The unique design of the X-STOP® implant enables it to be inserted using a minimally invasive approach, without fixation to bones or ligaments. Due to its minimally invasive nature, the procedure can typically be performed in 45 to 90 minutes.

According to an independent market research organization, there are approximately 1.4 million individuals in the United States with a primary or secondary diagnosis of lumbar spinal stenosis. The X-STOP® IPD® procedure may be a treatment alternative for approximately 220,000 of these individuals who would have otherwise been treated with conservative non-operative therapies or with a surgical procedure called a laminectomy.

About Kyphon Inc.

Kyphon develops and markets medical devices designed to restore and preserve spinal function and diagnose the source of low back pain using minimally invasive technologies. The company's products are used in balloon kyphoplasty for the treatment of spinal fractures caused by osteoporosis or cancer, in the Functional Anaesthetic Discography™ (F.A.D.™) procedure for diagnosing the source of low back pain, and in the Interspinous Process Decompression (IPD®) procedure for treating the symptoms of lumbar spinal stenosis. More information about the company and its products can be found at www.kyphon.com and its balloon kyphoplasty patient education Web site, www.spinalfracture.com.

Functional Anaesthetic Discography and F.A.D. are trademarks, and Kyphon, X-STOP, and IPD
are registered trademarks, of Kyphon Inc.

Contact Information

Investors and Media
Julie D. Tracy
Vice President, Chief Communications Officer
408-548-6687
jtracy@kyphon.com

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